Staburo contributes to bioinformatic analysis in psoriasis phase 2 study 

We are pleased that part of our work has been published as a letter to the author in the Journal of investigative dermatology. 

In this publication we supported the bioinformatic analysis in a study investigating the effect of spesolimab on microRNA expression in generalized pustular psoriasis (GPP). It was the first time investigating the role of microRNAs in both skin and blood samples of patients with GPP. 

Staburo assisted in data analysis and visualisation as well as in biological interpretation and identified a set of 5 core microRNA that showed consistent dysregulation in GPP and modulation upon spesolimab treatment. 

DOI: 10.1016/j.jid.2025.08.020     

Meet the Management – Lauri Õnnik– Director Data Management 

As Staburo continues to grow, so does our management team and with growth come new responsibilities and opportunities! We are excited to announce that Lauri Õnnik has been promoted to Director Data Management. 
We would like to introduce him as the newest member of our management team and give him the opportunity to share more about himself and his passions. 

Who are you?  

My name is Lauri Õnnik, and I am Director Data Management at Staburo. I joined the Staburo team in 2023 when Data Management services were introduced to the company’s portfolio. I studied Sports Science at the University of Tartu. 

Please tell us something about your area of work.  

Clinical Data Management focuses on collecting and cleaning clinical trial data ensuring the completeness and consistency of the data to be ready for programming and analysis.  

What are your goals for your role?  

My goal is to build a group of data management experts with a wide perspective on the field accompanied by strong collaboration both within the team but also across related functions. 

Would you like to learn more about the other directors? All previous interviews are linked below, offering insights into their stories and goals: Stefan Bentink, Habib Esmaeili, Katrin Frank, Lena Herich, Luciana Husfeld, Janine Roy, Laura Schlieker and Angelika Böhm. 

Staburo at Wiesn 2025

On 25 September 2025, the Staburo GmbH team came together to enjoy a fun evening at the Oktoberfest in Munich. This yearly tradition was a wonderful opportunity to connect beyond the usual work environment, as employees, including many of our remote colleagues, gathered in person to share an unforgettable day. 

Alongside a few clients, we enjoyed the unique Oktoberfest atmosphere with traditional Bavarian food, music and, of course, a few beers. The lively conversations and shared experiences highlighted the strong relationships that make collaboration at Staburo so successful. 

Some colleagues even embraced the festive spirit further by heading to the rollercoasters and rides after the tent celebrations. 

Events like these are an important part of our company culture, bringing people together and strengthening partnerships. We’re already looking forward to next year’s Wiesn! 

New R Package in Staburo: shadowVIMP – A Variable Selection Method for Random Forests 

At Staburo, we’re committed to developing solutions to statistical challenges that go beyond standard methods – supporting both client projects and scientific progress. 

A recent example of this commitment is shadowVIMP, a novel variable selection method based on random forest importance measures and permutation testing. Developed in-house by our colleagues Tim Müller, Hannes Buchner, and Maria Blanco, together with Dr. Roman Hornung, Ludwig Maximilian University of Munich, Germany, the method was met with great interest at conferences in Vienna and Berlin. 

ShadowVIMP adresses key challenges in high-dimensional data analysis, especially when variables are correlated – a known issue of the random forest variable importance measure. By preserving the correlation structure in the permutations and adjusting for multiple testing, it aims to offer more reliable and interpretable variable selections for exploratory analyses. 

We’re pleased to share that the method has been implemented as an open-source R package by Oktawia Miluch and Tim Müller, which is now available on CRAN. 

This work is one example of how we invest in methodological development to challenges we face in our project work. If you’re interested in collaborating on applied methodology – or in joining a team that values your statistical expertise – we’d love to hear from you. 

• Explore the package on CRAN 

• Interested in working with us? Contact us via the button below.

Strategy Workshop & Summer Party 2025

Earlier this month, the Staburo team gathered for a full-day strategy workshop followed by our much-anticipated summer party. In the morning, we joined our workshop groups previously assigned. Topics such as: Ethical and Respectful Leadership, Empathetic and Supportive Culture, Growth and Development, Empowerment and Autonomy, and Strategic and Sustainable Business Focus were discussed to explore how we live our values and sharpen our strategy for the months ahead. Lively debates yielded a set of clear recommendations that will guide our priorities.

This year we also introduced a poster challenge: each group gathered their top recommendations onto creative, eye-catching posters. By lunch time, they brought their concepts to life in colourful visuals, infographics and snappy taglines. In a lively end-of-workshop showcase, participants toured each display, asked questions and voted for their favourites.

After our working day, we moved into the ground-floor courtyard for our summer party. The barbecue was fired up for party and conversations started to flow. Even a sudden rain shower couldn’t dampen spirits – instead, colleagues and family members settled under umbrellas and on the inside venue, cheering each other on through photo challenges, lawn games and table tennis.

Whether in focused workshops or festivities, nothing brings us closer than the chance to learn, grow and celebrate together. Here’s to putting our new insights into action and to many more memorable moments at Staburo!