Staburo at the 9th Pharm-Tox Summit in Munich 

Imagine you are tasked with designing a phase II dose finding study to come up with a suitable dose for phase III. To accomplish this, the invited talk by Gabriele Bleckert from Staburo GmbH at the 9th German Pharm-Tox Summit in Munich on 14 March 2024 within the AGAH session gave good directions.

Ten years ago, the Multiple Comparison Procedure and Modelling (MCP-Mod) Methodology was qualified by regulators as an efficient statistical methodology for model-based design and analysis of phase II dose finding studies under model uncertainty.

The talk showcased two clinical trials in the indication Schizophrenia and Diabetes where MCP-Mod has been implemented successfully. MCP-Mod was motivated and key features of the methodology were explained with focus on MCP-Mod at analysis stage. Planning of MCP-Mod trials was elaborated in the subsequent talk by Sebastian Bossert from Boehringer Ingelheim.

Many thanks to Ruwen Böhm and Barbara Schug from SocraTec who chaired the AGAH (Arbeitsgemeinschaft für Angewandte Humanpharmakologie e. V.) session for inviting us to share our insights on MCP-Mod. Special thanks to Sebastian Bossert for the illuminating exchange on MCP-Mod.

Februar team get togethers

February is already over, and we look back on some smaller, but great and fun team get togethers in our office. As we continue to grow, it is always important that we create time and opportunities to get to know each other and exchange ideas.

Beginning of the months we celebrated the carnival season with fresh doughnuts (German: Krapfen) in the office and enjoyed a relaxed coffee break together.

A few weeks later this was followed by one of our monthly office days plus another movie night for all colleagues. On this day also a lot of our remote colleagues travelled to our office in Munich, and we had the chance to celebrate the 10th anniversary of one of our colleagues.

As we have ‘Big Lebowski’ fans in our team, this film was on the programme and was accompanied by a presentation about the most important characters in the run-up to the film. We spent an entertaining und funny evening together including pizza and drinks.

We always look forward to meeting our colleagues in our office – either for business meetings or for smaller after work events. Thanks for your great participation.