Staburo Managing Director Hannes Buchner will give a talk about “Applied Biomarker analyses in drug development. Lasso, random forest, longitudinal biomarker analyses” at the colloquium “Statistische Methoden in der empirischen Forschung” (“Statistical methods in empirical research”) at the Freie Universität Berlin on February 14, 2023.
The presentation is a collaboration of our Staburo employees Laura Schlieker, Armin Ott, Stephan Bischofberger and Gabriele Bleckert and will provide insight into how random forests, LASSO and IPF-LASSO (Integrated LASSO with Penalty Factors) can be applied to investigate the prognostic and predictive potential of high dimensional biomarker data by using training and test data principles, subsampling methods and permutation concepts. In addition, the application of mixed models with repeated measurements and the concept of sliding regression for analyses of longitudinal biomarker data and their pharmacodynamic features will be addressed.
At the colloquium, which is organised by a committee of members of various institutions and companies, such as Pfizer, Bayer, Parexel and Cytel, speakers from academia and industry present current topics in biostatistics, medicine, epidemiology, agriculture, or other fields of application once a week. It is open to the public and all those interested in empirical research and statistical research are welcome to attend in person or virtually! More information can be found on the institute’s website.
We look forward to numerous listeners and to welcome you within the audience!
